Department of Chemistry & Biochemistry

Dr. Sophia.D

Assistant Professor, HOD (Biochemistry)

  • Academic Experience:

    9+ years, Teaching Experience:7 years

  • Qualification:

    M.Sc., M.Phil., Ph. D

  • Contact:

    Email: sophiad@jyotinivas.org

Dr. Sophia.D

Assistant Professor, HOD (Biochemistry)

# Degree Subject University, place ,year
1 Ph.D in Biochemistry Karpagam University, Coimbatore Karpagam University, Coimbatore, 2013
2 M.Phil in Biochemistry Avinashilingam University, Coimbatore Avinashilingam University, Coimbatore, 2004
3 Ph.D in Biochemistry Karpagam University, Coimbatore Karpagam University, Coimbatore, 2013
4 M.Sc in Biochemistry Periyar University, Salem Muthayammal College of Arts and Science, Namakkal, 2003
5 B.Sc in Biochemistry Bharathidasan University, Trichy Holycross college, Trichy, 2001

Research Experience – 7 years Principal investigator for a minor research project on “Green synthesis of silver nanoparticles from the leaves of Citrus limon and its in vitro α-glucosidase and α-amylase inhibitory activities” funded by the University Grant Commission of India (UGC) and was awarded Rs.1,85,000/- to pursue the research.
• Principal investigator for a minor research project on “Antiproliferative and Anticancer Activity of Phyto fabricated Silver Nanoparticles from Citrus limon Leaf Extract against Breast Cancer Cells” funded by Department of Science and Technology, Govt. of Karnataka and was awarded Rs. 30,000/- to pursue the research.
Ph.D in Biochemistry, Karpagam University, Coimbatore, 2009-2012. Title of the project: Protective effect of Emilia sonchifolia on azaserine and high protein diet induced pancreatic dysplasia in albino rats.
M.Phil in Biochemistry, Avinashilingam University, Coimbatore, 2003-2004. Title of the project: Antidiabetic effect of Cyperus rotundus on streptozotopcin-induced albino rats

Chella Perumal Palanisamy, Vinoth Prasanna Gunasekaran, Sophia Dominic, and Tran Dang Xuan, Phenolic Allelochemicals from Crops and Weed Management. Plant Phenolics in Sustainable Agriculture, Springer Nature Singapore Pte Ltd. 2020 R. Lone et al. (eds).
An Insight into Traditional and Integrative medicine in EAI/SPRINGER INNOVATIONS IN COMMUNICATION AND COMPUTING - Translating Healthcare through Intelligent Computational Methods, Springer Nature Switzerland (Accepted)

Sophia, D., P. Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2012. Antioxidant properties of Emilia sonchifolia -An in vitro study. Journal of Pharmacy Research, 5:1162-1164.
Sophia, D., P. Ragavendran, C. Arulraj and V.K.Gopalakrishanan, 2012. Protective effect of Emilia sonchifolia(L.) against high protein diet induced oxidative stress in pancreas of
Wistar rats. Journal of Pharmacy and Bioallied Sciences, 4: 60-65.
Sophia, D., P.Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2011. In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.) DC. Journal of Basic and Clinical Pharmacy, 2: 179 - 183.
Sophia, D., P. Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2011. High protein diet induced hepatic oxidative stress and its amelioration by the herb, Emilia sonchifolia(L.)DC. Pharmacologyonline, 1: 149- 154.
Sophia, D., M. Gomathy, T. Shebin, P. Ragavendran, C. Arulraj, V.K. Gopalakrishnan, 2011. Effect of Emilia sonchifolia (Linn.) DC on alcohol- induced oxidative stress in pancreas of male albino rats. Asian Pacific Journal of Tropical medicine, 973-977.
Sophia D and V.K. Gopalakrishnan, 2011. Anti-carcinogenic effect of Emilia sonchifolia (L) DC. In azaserine - induced pancreatic cancer in Albino rats. Journal of Carcinogenesis, 10:15.
Ragavendran. P, D. Sophia, C. Arulraj, V. K. Gopalakrishnan, 2012. Cardioprotective effect of Aqueous, Ethanol and Aqueous ethanol extract of Aerva lanata (Linn.) against doxorubicin induced cardiomyopathy in rats. Asian Pacific Journal of Tropical Biomedicine, 1-7.
Ragavendran, P, D. Sophia, C. Arul Raj, T. Starlin and V. K. Gopalakrishnan, 2012. Evaluation of enzymatic and non-enzymatic antioxidant properties of Aerva lanata (l) - an invitro study. International Journal of Pharmacy and Pharmaceutical Sciences 4: 522 -526.
Ragavendran, P, D.Sophia, C.Arul Raj, T. Starlin and V.K.Gopalakrishnan, 2012. Phytochemical screening, antioxidant activity of Aerva lanata (L.) - an in vitro study. Asian Journal of Pharmaceutical and Clinical Research 5: 77 - 81.
Arul Raj, C, P. Ragavendran, D. Sophia, M.A. Rathi and V.K.Gopalakrishnan, 2012. Evaluation of in vitro antioxidant and anticancer activity of Alpinia purpurata. Chinese Journal of Natural Medicine 10: 263 -268.
Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Gomathi, D. Sophia, C. Arul Raj, C. Uma and K. Kalaivani, 2012. In vivo and in vitro antitumor activity of Jasminum sambac (L.) Ait oleaceae flower against Dalton's ascites lymphoma induced swiss albino mice. International Journal of Pharmacy and Pharmaceutical Sciences., 4: 144 - 147.
Ragavendran, P, D.Sophia, C.Arul Raj, and V.K.Gopalakrishnan, 2011. Functional group analysis of various extracts of Aerva lanata (L.,) by FTIR spectrum. Pharmacologyonline 1: 358-364.
Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Gomathi, D. Sophia, C. Arul Raj, C. Uma and K. Kalaivani, 2011. Acute and sub-chronic toxicity effect of Jasminum sambac (L.) Oleaceae flower in swiss albino mice. Pharmacologyonline., 3: 517 - 525.
Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Sophia, D. Gomathi, C. Arul Raj, D. Guru Kumar, C. Uma and K. Kalaivani, 2011. In vitro free radical scavenging activity of Jasminum sambac (L.) Ait oleaceae flower. Asian Journal of Pharmaceutical and Biological Research., 1: 370 - 375.
Kalaiselvi, M., R. Narmadha, P. Ragavendran, C. Arul Raj, D. Sophia, G. Ravikumar, D. Gomathi, C. Uma and K. Kalaivani, 2011. In vivo simulated in vitro model of Jasminum sambac (L.) using mammalian liver slice technique. Asian Pacific Journal of Tropical Biomedicine., 2: 216 - 219.
Lisina K.V, P. Ragavendran, D. Sophia, S. Rajamanikandan, T. Sindhu, D. Durgapriya and V.K. Gopalakrishnan, 2011. A comparative study of Justicia adhatoda, Mimosa pudica and Vitex negundo against hepatoprotective activity in albino rats - in vivo evaluation. Pharmacologyonline 1: 481-491.
Suganya, S, D. Sophia, C. Arul Raj, M. A. Rathi, L. Thirumoorthi, P. Meenakshi, D. Guru Kumar and V. K. Gopalakrishnan, 2011. Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta. Pharmacognosy Research 3: 201 - 207.
Rajamanikandan S , T. Sindhu, D. Durgapriya, D. Sophia, P. Ragavendran and V.K. Gopalakrishnan, 2011. Radical scavenging and antioxidant activity of ethanolic extract of Mollugo nudicaulis by in vitro assays. Indian Journal of Pharmaceutical Education and Research 45: 310 - 316.
ArulRaj. C, S. Umashankari, B. R. Menon, M. A. Rathi, P. Meenakshi, D. Gurukumar, D. Sophia, P. Ragavendran, V. K. Gopalakrishnan, 2010. Ceiba pentandra (l.) Leaves Inhibits Perchloroethylene - Induced Hepatic Damage in Rats. International Journal of Biomedical Research and Analysis, 1 : 72-75.
Sindhu, T, S. Rajamanikandan, P. Ragavendran, D. Sophia, P. Meenakshi, D. Durgapriya and V.K. Gopalakrishnan, 2010. Antidiabetic activity of Mollugo nudicaulis against alloxan induced diabetic rats. International Journal of Applied Biology and Pharmaceutical Technology 1: 511 - 519.
Sophia D., Divya Joseph, 2015. Evaluation of in vitro cytotoxic effects of Symplocos cochinchinensis against HeLa and MCF7 cell lines. National Journal of Jyoti Research academy, 9: 52-55.
Sophia, D., P. Ragavendran, C.Arulraj and V.K.Gopalakrishanan. 2014. Protective effect of Emilia sonchifolia on azaserine-induced pancreatic dysplasia. Journal of Acute Medicine, 4 : 68-74.
In silico docking analysis of Emilia sonchifolia(L.)DC. gas chromatography - mass spectroscopy derived terpenoid compounds against pancreatic cancer targets (AKT and BRCA2).World Journal of Pharmacy and Pharmaceutical Sciences,2014,3, 1844-1855.
C. Arul Raj , P. Ragavendran , D. Sophia, T Starlin, M. A. Rathi, V.K. GopalakrishnanEvaluation of in vitro enzymatic and non-enzymatic antioxidant properties of leaf extractfrom Alpinia purpurata (Vieill.) K. Schum., Chinese Journal of Integrative Medicine, 2016, 22, 691-695. (Springer).

Presented a paper on "In vitro antioxidant potential of n-hexane extract of whole plant Emilia Sonchifolia in 3rd Annual Research Congress held at Karpagam University on 9th to 10th December 2011.
Presented a paper entitled "Molecular Biology of head and neck cancer" in National Seminar on "Deterrence of cancer" held at Karpagam University on 28th October 2011.
Presented a poster in the International conference on "Frontiers in carcinogenesis and cancer prevention: Scientific Advances and public Health Initiatives" organised by Carcinogenesis Foundation held at Dayananda Sagar Institutions, Bangalore on 16th to 18th February 2011.
Presented a paper in the 30th Annual convention of Indian Association for cancer research and International symposium on "Signaling network and cancer" held at Indian institute of chemical biology, Kolkata on 6th to 9th February 2011.
Presented a paper on "Protective effect of Emilia Sonchifolia against raw soy flour induced pancreatic cancer" in the 2nd Annual Research Congress held at Karpagam University on 8th to 11th December 2010.
Presented a paper in the National level seminar on 'Global strategies in Biological Sciences", 2003, Muthayammal college of Arts and Science, Tamilnadu.
Presented a poster on ‘Mangroves Ecosystem - Its Importance , Threats And Future Implementations To Conserve It’in the Online International Conference on “Climate Change, Mangroves and Sustainable Management” organized by IQAC & PG-Department of Botany of Shri Pancham Khemraj Mahavidyalaya, Sawantwadi, (MS) University of Mumbai, Mangrove Society of India & Sahyadri Botanical Society, Kolhapur on 24th April 2020.
Presented a paper on “ Green synthesis of silver nanoparticles using Citrus limonleaves” in International Conference on Nanomaterials and their Applications, Universityof Mysore, Mysore, 1st&2nd March, 2018.
Presented a paper entitled “Ayurveda For A Healthy Life” in the Two days Virtual International Conference on ‘Research Interventions and Advancements in Plant Science’ (RIAPS 2020) on 15th and 16th June, 2020 organised by Sadguru Gadage Maharaj College, Karad “NAAC Re- Accredited A Grade” (Autonomous) College and Shri Pancham Khemraj Mahavidyalaya, Sawantwadi, (MS) “NAAC Re-Accredited A Grade” College, Sawantwadi, India.
Presented a poster on ‘Mangroves Ecosystem - Its Importance, Threats And Future Implementations To Conserve It’ on Climate Change, Mangrove & Sustainable Management organised by IQAC & PG-Department of Botany of Shri Pancham Khemraj Mahavidyalaya, Sawantwadi, (MS) University of Mumbai, Mangrove Society of India & Sahyadri Botanical Society, Kolhapur on 24th April 2020. Published in Climate Change, Mangrove & Sustainable Management. ISBN: 978-93-88901-10-9, First Edition 2020, Pg No: 163, Bhumi Publishing India.
Presented a poster on ‘The role of research and development against coronavirus’ in Virtual International Poster Conference on COVID -19: Impact and Response organised by Karamveer Hire Arts, Science, Commerce and Education College, Gargoti. District, Kolhapur, Maharashtra, India, on 12-13 June 2020. Published in Book of posters ISBN No: 978-93-88901-13-0. First Edition 2020, Bhumi Publishing India.

Attended a lecture delivered by the Nobel Laureate “Sir Venkatraman Ramakrishnan “ at St.Joseph’s College Autonomous on 19th January 2019.
Participated in “Nano for Youth” programme as a part of “International Conference on Nanoscience and Technology” conducted by IISc Bengaluru on 22nd March 2018.
Participated in the International Conference on Electronics, Physics and Chemistry – 2017 held at Jyoti Nivas College Autonomous, Bangalore, India on Feb 16 – 18, 2017 in collaboration with International Multidisciplinary Research Foundation (IMRF).
Recent Trends in Chemistry' - UGC sponsored National Conference on 24th February 2016 Participated as member of organizing committee in Jyoti Nivas College Autonomous, Bangalore
Participated in the third Indian Youth Sciences congress held at the NASC complex, New Delhi on 3rd to 5th November 2011.
Participated in one day state level symposium on "Immunology of infectious diseases" held at Karpagam University on 19th February 2010.
Participated in the International Symposium on "Frontiers in carcinogenesis and Cancer Prevention: Scientific Endeavors and Public Health Initiatives" held at Reliance life sciences at Dhirubhai Life Sciences centre, Mumbai, on 5th to 7th February 2010.
Participated in the workshop on "Modern Chromatographic Techniques" held at Karpagam University , Coimbatore, Tamilnadu, on 21st and 23rd November 2009.
Participated in orientation programme on "Emerging trends in Pharmaceutical Analytical methods", organized by Karpagam University, Coimbatore,Tamilnadu from September 4th & 5th 2009.
Participated in "EDUCATION FOR ALL" (Sarva Shiksha Abhiyan) held at Karadimadai, Coimbatore on 10th October 2002.
Participated in the National level seminar on "Current trends and future direction in life science", 2002, Muthayammal college of Arts and Science, Tamilnadu.
Participated in the workshop on Medical laboratory technology, July2000, Seahorse Hospitals, Trichy, Tamilnadu.
Participated in Special Camp (NSS) on "Watershed Management and Waste Land Devolopment" held at Thayanur, Thiruchirappalli district from 8th to 17th June 1999.

Delivered a talk on “ Biochemistry of Stress and Role of Biosensors In Stress Management -Live Webinar Series” organized by Dr.NGP College of Technology, Coimbatore in association with MHRD- Institution’s Innovative Council (IIC) on 19th May 2020.

Basic knowledge in computer functioning, MS Office.

Completed “Psychological First Aid” a certificate course authorized by Johns Hopkins University
Completed Short Term E-Course on Applied Zoology organized by Department of Zoology of Baburao Patil College of Arts and Science, Solapur on 29th April – 3rd May 2020.
Completed the Training Program Requirement For Foundation Diploma In Naturopathyby THE KEW TRAINING ACADEMY -Accredited by CTAA - Complementary Therapists Accreditation Association on 8th May 2020.
Completed course 15 week Swayam MOOC course on “Functional foods and nutraceuticals” on 29th September 2020
Ten Week Course on ‘Essentials of Global Health’ an online course authorized by Yale University on 6th July 2020.
Four Week Course on ‘Biohacking Your Brain's Health’ an online course authorized by Emory University on 31st May 2020.
Six Week Course on ‘Introduction to Psychology’ an online course authorized by Yale University on 30th May 2020.
Six Week Course on ‘The Science of Gastronomy’ an online course authorized by The Hong Kong University of Science and Technology on 26th May 2020.
Four Week Course on ‘Grammar and Punctuation’ an online course authorized by University of California, Irvine on 25th May 2020.
Six Week Course on ‘The Arts and Science of Relationships: Understanding Human Needs’ an online course authorized by University of Toronto on 25th May 2020.

A minor research project entitled 'Green synthesis of silver nanoparticles from the leaves of Citrus limon and its in vitro ∝-glucosidase and ∝- amylase inhibitory activities' awarded by the UGC with a grant amount of Rs.1,85,000 by UGC (MRP (S) 13- 14/ KABA021/UGC-SWRO
Awarded an amount of Rs. 30,000/ by Department of Science and Technology, Govt. of Karnataka to pursue a short-term study on “Antiproliferative and Anticancer Activity of Phyto fabricated Silver Nanoparticles from Citrus limon Leaf Extract against Breast Cancer Cells”.

Two day online Faculty Development Programme on “Emerging Web Based Pedagogical Practices” organized by Annammal College of Education for Women, Thoothukudi on 20th& 21st May 2020.
Webinar on “Arts of writing Scientific Reports” organized by Velammal Engineering College Autonomous, Chennai on 14th and 15th May2020.
National Level Online Webinar on “Doctoral Thesis: Key Components and Research Skills” and “Research Funding Opportunities: In India and Abroad” Organized by IQAC & Research Cell organized by SM Shetty college of Science, Commerce and Management Studies, Mumbai on 14th May 2020.
Faculty Development Programme on “E-Content Preparation -Finding copyright free images and sounds” organized by Loyola College of Education , Chennai in association with Universal Teachers Academy on 13th May 2020.
Online Faculty Development Programme on “The Art of Teaching” organized by NallamuthuGounder Mahalingam College (Autonomous), Coimbatore on 12th May 2020.
Six Day International Faculty Development Programme titled Novel Materials for Energy and Biomedical (Covid-19) Healthcare Applications organized by Department of Science & Humanities, M.Kumarasamy College of Engineering, Karur from 11th - 16th May 2020.
Faculty Development Programme on “ Challenges In Building Collaborations In Research and Innovation” organized by Dr. M.G.R Educational and Research Institute (Deemed to be University), Chennai on 9th May 2020.
One day Faculty development Programme on “Supply chain management during a pandemic’organized by VET Institute of Arts and Science, Erodeon 9th May 2020.
One day Faculty development Programme on “Google Meet -101” organized by VET Institute of Arts and Science, Erodeon 8th May 2020.
Webinar on “Challenges and opportunities for family in this Corona Virus pandemics organized by Moolji Jaitha College, Jalgaon, North Maharashtra on 7th May 2020.
Webinar on “Gamification Tools in Teaching” organized by Internal Quality Assurance Cell, St. Xavier’s College for Women, Aluva on 7th May 2020.
Three day Virtual Faculty Development Programme on "Enhancing Excellence in Higher Education Through Assessment and Accreditation" organized by IQAC, Sree Narayana Guru College in association with IQAC, Kristu Jayanti College, Bengaluru from 6th - 8th May 2020.
Webinar on “How to be a structural instructional designer in e-learning” organized by Department of computer technology, PSG college of Arts and Science Autonomous on 6th May 2020
National Webinar on “Use of Elsevier Tools in Research Workflow” organized by the Department of Commerce, of Madras, Chennai and Elsevier on 5th May, 2020.
Webinar on How to Use Turnitin Software for your Research “Turnitin Online on Campus” organized by Guru Nanak Institute of Management Studies, on 4th May 2020
Online National Conference on ‘Applications of Quantum Chemistry’ jointly organized by IQAC and Department of Chemistry, Shri Pancham Khemraj Mahavidyalaya, Sawantwadi on 3rd May 2020.
Webinar on “How to be a Successful Instructional Designer in E-Learning” organized by Rathnam Institute of Management, Coimbatore on 30th April 2020.
Faculty Development Programme on "Art of Writing Research Article in Hi-Indexed Journals" organized by the Department of Business Administration of Nehru Arts and Science College, Coimbatore on 29th& 30th April 2020.
One week National level Faculty orientation Workshop on Revised Guidelines of NAAC organized by IQAC cell, Yashavantrao, Chavan Institute of Science Autonomous, Satara, Maharashtra from 27th April -2nd May 2020.
Five day Virtual Faculty Development Programme on Recent Trends In Biomedical Engineering-Research Perspective in association with MHRD-IIC and IQAC organized by Department of Biomedical engineering, Dr.NGP College of Technology, Coimbatore from 26th -30th April 2020.
Webinar entitled “Anthropological Understanding of COVID-19”organized by Shiksha SanskritiUtthanNyas (SSUN) Tamil Nadu on 27th April 2020.
Webinar on “How to tackle Covid -19 with health practices? organized by Vivekanandha College of Arts and Science for Women ,Salem, Tamilnadu on 25th April 2020.
Two-day International Online Workshop on “Let’s dock to dock Corona” conducted by the Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam on 18th and 19th April, 2020.