Department of Chemistry & Biochemistry

NAME: Dr. D.Sophia
POST: Lecturer in Biochemistry,
ADRESS:Jyoti Nivas Degree College (Autonomous), Bangalore E.MAIL ID: sophiatino@gmail.com
Qualification:M.Sc., M.Phil., Ph. D

Academic Experience: 5 years

EDUCATIONAL QUALIFICATIONS

COURSE BOARD/UNIVERSITY INSTITUTION YEAR OF PASSING
Ph.D in Biochemistry Karpagam University, Coimbatore Karpagam University, Coimbatore 2013
M.Phil in Biochemistry Avinashilingam University, Coimbatore Avinashilingam University, Coimbatore 2004
M.Sc in Biochemistry Periyar University, Salem Muthayammal College of Arts and Science, Namakkal 2003
B.Sc in Biochemistry Bharathidasan University, Trichy Holycross college, Trichy 2001

PROFESSIONAL EXPERIENCE

- Lecturer, Department of Biochemistry, Jyoti Nivas Degree College, Banglore (2013 - till date).
- Lecturer, Department of Biochemistry, Vishwa Bharathi PG College, Hyderabad (2006 - 2007).
- Lecturer, Department of Chemistry, Christ the King Polytechnic College, Coimbatore (2004 - 2005).


RESEARCH EXPERIENCE - 4 YEARS
- Ph.D in Biochemistry, Karpagam University, Coimbatore, 2009-2012. Title of the project: Protective effect of Emilia sonchifolia on azaserine and high protein diet induced pancreatic dysplasia in albino rats.

- M.Phil in Biochemistry, Avinashilingam University, Coimbatore, 2003-2004. Title of the project: Antidiabetic effect of Cyperus rotundus on streptozotopcin-induced albino rats

PAPER PUBLICATIONS - 20

Sophia, D., P. Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2012. Antioxidant properties of Emilia sonchifolia -An in vitro study. Journal of Pharmacy Research, 5:1162-1164.

Sophia, D., P. Ragavendran, C. Arulraj and V.K.Gopalakrishanan, 2012. Protective effect of Emilia sonchifolia(L.) against high protein diet induced oxidative stress in pancreas of

Wistar rats. Journal of Pharmacy and Bioallied Sciences, 4: 60-65.

Sophia, D., P.Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2011. In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.) DC. Journal of Basic and Clinical Pharmacy, 2: 179 - 183.

Sophia, D., P. Ragavendran, C.Arulraj and V.K.Gopalakrishanan, 2011. High protein diet induced hepatic oxidative stress and its amelioration by the herb, Emilia sonchifolia(L.)DC. Pharmacologyonline, 1: 149- 154.

Sophia, D., M. Gomathy, T. Shebin, P. Ragavendran, C. Arulraj, V.K. Gopalakrishnan, 2011. Effect of Emilia sonchifolia (Linn.) DC on alcohol- induced oxidative stress in pancreas of male albino rats. Asian Pacific Journal of Tropical medicine, 973-977.

Sophia D and V.K. Gopalakrishnan, 2011. Anti-carcinogenic effect of Emilia sonchifolia (L) DC. In azaserine - induced pancreatic cancer in Albino rats. Journal of Carcinogenesis, 10:15.

Ragavendran. P, D. Sophia, C. Arulraj, V. K. Gopalakrishnan, 2012. Cardioprotective effect of Aqueous, Ethanol and Aqueous ethanol extract of Aerva lanata (Linn.) against doxorubicin induced cardiomyopathy in rats. Asian Pacific Journal of Tropical Biomedicine, 1-7.

Ragavendran, P, D. Sophia, C. Arul Raj, T. Starlin and V. K. Gopalakrishnan, 2012. Evaluation of enzymatic and non-enzymatic antioxidant properties of Aerva lanata (l) - an invitro study. International Journal of Pharmacy and Pharmaceutical Sciences 4: 522 -526.

Ragavendran, P, D.Sophia, C.Arul Raj, T. Starlin and V.K.Gopalakrishnan, 2012. Phytochemical screening, antioxidant activity of Aerva lanata (L.) - an in vitro study. Asian Journal of Pharmaceutical and Clinical Research 5: 77 - 81.

Arul Raj, C, P. Ragavendran, D. Sophia, M.A. Rathi and V.K.Gopalakrishnan, 2012. Evaluation of in vitro antioxidant and anticancer activity of Alpinia purpurata. Chinese Journal of Natural Medicine 10: 263 -268.

Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Gomathi, D. Sophia, C. Arul Raj, C. Uma and K. Kalaivani, 2012. In vivo and in vitro antitumor activity of Jasminum sambac (L.) Ait oleaceae flower against Dalton's ascites lymphoma induced swiss albino mice. International Journal of Pharmacy and Pharmaceutical Sciences., 4: 144 - 147.

Ragavendran, P, D.Sophia, C.Arul Raj, and V.K.Gopalakrishnan, 2011. Functional group analysis of various extracts of Aerva lanata (L.,) by FTIR spectrum. Pharmacologyonline 1: 358-364.

Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Gomathi, D. Sophia, C. Arul Raj, C. Uma and K. Kalaivani, 2011. Acute and sub-chronic toxicity effect of Jasminum sambac (L.) Oleaceae flower in swiss albino mice. Pharmacologyonline., 3: 517 - 525.

Kalaiselvi, M., R. Narmadha, P. Ragavendran, G. Ravikumar, D. Sophia, D. Gomathi, C. Arul Raj, D. Guru Kumar, C. Uma and K. Kalaivani, 2011. In vitro free radical scavenging activity of Jasminum sambac (L.) Ait oleaceae flower. Asian Journal of Pharmaceutical and Biological Research., 1: 370 - 375.

Kalaiselvi, M., R. Narmadha, P. Ragavendran, C. Arul Raj, D. Sophia, G. Ravikumar, D. Gomathi, C. Uma and K. Kalaivani, 2011. In vivo simulated in vitro model of Jasminum sambac (L.) using mammalian liver slice technique. Asian Pacific Journal of Tropical Biomedicine., 2: 216 - 219.

Lisina K.V, P. Ragavendran, D. Sophia, S. Rajamanikandan, T. Sindhu, D. Durgapriya and V.K. Gopalakrishnan, 2011. A comparative study of Justicia adhatoda, Mimosa pudica and Vitex negundo against hepatoprotective activity in albino rats - in vivo evaluation. Pharmacologyonline 1: 481-491.

Suganya, S, D. Sophia, C. Arul Raj, M. A. Rathi, L. Thirumoorthi, P. Meenakshi, D. Guru Kumar and V. K. Gopalakrishnan, 2011. Amelioration of nitrobenzene-induced nephrotoxicity by the ethanol extract of the herb Euphorbia hirta. Pharmacognosy Research 3: 201 - 207.

Rajamanikandan S , T. Sindhu, D. Durgapriya, D. Sophia, P. Ragavendran and V.K. Gopalakrishnan, 2011. Radical scavenging and antioxidant activity of ethanolic extract of Mollugo nudicaulis by in vitro assays. Indian Journal of Pharmaceutical Education and Research 45: 310 - 316.

ArulRaj. C, S. Umashankari, B. R. Menon, M. A. Rathi, P. Meenakshi, D. Gurukumar, D. Sophia, P. Ragavendran, V. K. Gopalakrishnan, 2010. Ceiba pentandra (l.) Leaves Inhibits Perchloroethylene - Induced Hepatic Damage in Rats. International Journal of Biomedical Research and Analysis, 1 : 72-75.

Sindhu, T, S. Rajamanikandan, P. Ragavendran, D. Sophia, P. Meenakshi, D. Durgapriya and V.K. Gopalakrishnan, 2010. Antidiabetic activity of Mollugo nudicaulis against alloxan induced diabetic rats. International Journal of Applied Biology and Pharmaceutical Technology 1: 511 - 519.

PAPERS PRESENTED - 6
Presented a paper on "In vitro antioxidant potential of n-hexane extract of whole plant Emilia Sonchifolia in 3rd Annual Research Congress held at Karpagam University on 9th to 10th December 2011.

Presented a paper entitled "Molecular Biology of head and neck cancer" in National Seminar on "Deterrence of cancer" held at Karpagam University on 28th October 2011.

Presented a poster in the International conference on "Frontiers in carcinogenesis and cancer prevention: Scientific Advances and public Health Initiatives" organised by Carcinogenesis Foundation held at Dayananda Sagar Institutions, Bangalore on 16th to 18th February 2011.

Presented a paper in the 30th Annual convention of Indian Association for cancer research and International symposium on "Signaling network and cancer" held at Indian institute of chemical biology, Kolkata on 6th to 9th February 2011.

Presented a paper on "Protective effect of Emilia Sonchifolia against raw soy flour induced pancreatic cancer" in the 2nd Annual Research Congress held at Karpagam University on 8th to 11th December 2010.

Presented a paper in the National level seminar on 'Global strategies in Biological Sciences", 2003, Muthayammal college of Arts and Science, Tamilnadu.

SEMINARS/CONFERENCES/WORKSHOPS ATTENDED - 9
'Recent Trends in Chemistry' - UGC sponsored National Conference on 24th February 2016 Participated as member of organizing committee in Jyoti Nivas College Autonomous, Bangalore

Participated in the third Indian Youth Sciences congress held at the NASC complex, New Delhi on 3rd to 5th November 2011.

Participated in one day state level symposium on "Immunology of infectious diseases" held at Karpagam University on 19th February 2010.

Participated in the International Symposium on "Frontiers in carcinogenesis and Cancer Prevention: Scientific Endeavors and Public Health Initiatives" held at Reliance life sciences at Dhirubhai Life Sciences centre, Mumbai, on 5th to 7th February 2010.

Participated in the workshop on "Modern Chromatographic Techniques" held at Karpagam University , Coimbatore, Tamilnadu, on 21st and 23rd November 2009.

Participated in orientation programme on "Emerging trends in Pharmaceutical Analytical methods", organized by Karpagam University, Coimbatore,Tamilnadu from September 4th & 5th 2009.

Participated in "EDUCATION FOR ALL" (Sarva Shiksha Abhiyan) held at Karadimadai, Coimbatore on 10th October 2002.

Participated in the National level seminar on "Current trends and future direction in life science", 2002, Muthayammal college of Arts and Science, Tamilnadu.

Participated in the workshop on Medical laboratory technology, July2000, Seahorse Hospitals, Trichy, Tamilnadu.

Participated in Special Camp (NSS) on "Watershed Management and Waste Land Devolopment" held at Thayanur, Thiruchirappalli district from 8th to 17th June 1999.

COMPUTING SKILLS
- Basic knowledge in computer functioning, MS Office.

MINOR RESEARCH PROJECT
A minor research project entitled 'Green synthesis of silver nanoparticles from the leaves of Citrus limon and its in vitro ∝-glucosidase and ∝- amylase inhibitory activities' awarded by the UGC with a grant amount of Rs.1,85,000 by UGC (MRP (S) 13- 14/ KABA021/UGC-SWRO